Тип публикации: статья из журнала

Год издания: 2024

Идентификатор DOI: 10.15826/chimtech.2024.11.1.01

Ключевые слова: BIOCOMPATIBLE ATERIALS, poly-3-hydroxybutyrate, FUNCTIONALIZED LIGOMERS, aminolysis, POLYMER-OLIGOMER LENDS, biocompatibility

Аннотация: Oligomers of poly-3-hydroxybutyrate (PHB) were prepared by aminolysis of high molecular weight PHB with ethylenediamine and 1,4-diaminobutane. Polymer-oligomer blends (10, 30, and 50% content of the oligomers) were prepared as films by solution casting. As the content of oligomers increased, a gradual increase in the hydrophilicityПоказать полностьюof the polymer surface was observed, resulting reflected in the water contact angle decrease from 84° to 72-76°. In addition, a moderate decrease in elongation at break, Young's modulus, and tensile strength for the blends were observed as more oligomer was added to the film. Finally, the viability of NIH-3T3 mouse fibroblasts was higher compared to intact PHB when growing in non-prepared polymer/oligomer mixtures. These findings confirm the benefits of the introduction of a hydrophilic functionalized oligomer into the PHB matrix in terms of improving the biocompatibility of the resulting polymer/oligomer blends.

Журнал: Chimica Techno Acta

Выпуск журнала: Т.11, №1

Номера страниц: 202411101

ISSN журнала: 24095613

Место издания: Ekaterinburg

Издатель: Уральский федеральный университет им. первого Президента России Б.Н. Ельцина

• Boyandin Anatoly N. (Federal Research Center “Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences”)
• Dvoinina Ljublyana M. (Reshetnev Siberian State University of Science and Technology)
• Sukovatyi Aleksey G. (Siberian Federal University)
• Sukhanova Anna A. (Reshetnev Siberian State University of Science and Technology)
• Ertiletskaya Natalya L. (Federal Research Center “Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences”)

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