Тип публикации: статья из журнала

Год издания: 2024

Идентификатор DOI: 10.1134/S1070428024050063

Ключевые слова: 4-nitrosopyrazoles, dinitroso compounds, pyrazoles, oxidation, reduction, azo coupling

Аннотация: The behavior of <i>N</i>-Substituted 3,5-dimethyl-4-nitroso-1<i>H</i>-pyrazoles in oxidation, condensation, and reduction reactions was studied. The synthesized 4-aminopyrazole was acylated and diazotized with further azo coupling or the replacement of the amino group by iodine, as well as subjected to condensation with 4-nitrobenzaldehyde. The first condensation of nitrosopyrazole with 2,4-dinitrotoluene was demonstrated. As a result, new functionalized pyrazole derivatives were isolated. The structure of the novel pyrazoles was confirmed by IR and ¹H and ¹³C NMR spectroscopy, gas chromatography-mass spectrometry, and elemental analysis. The synthesized compounds hold promise for further research in medicine and pharmaceutical chemistry.

Журнал: Russian Journal of Organic Chemistry

Выпуск журнала: Т.60, №5

Номера страниц: 835-840

ISSN журнала: 10704280

Место издания: Санкт-Петербург

Издатель: Pleiades Publishing, Ltd. (Плеадес Паблишинг, Лтд)

• Bobrova A.V. (Reshetnev Siberian State University of Science and Technology)
• Golenko E.I. (Reshetnev Siberian State University of Science and Technology)
• Oberenko A.V. (Siberian Federal University)
• Ivanenko T.Y. (Institute of Chemistry and Chemical Technology, Siberian Branch, Russian Academy of Sciences (SB RAS), “Krasnoyarsk Science Center SB RAS” Federal Research Center SB RAS)
• Root E.V. (Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University)
• Suboch G.A. (Reshetnev Siberian State University of Science and Technology)

• Ядро РИНЦ (eLIBRARY.RU)